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Blow with air a good idea...vacuum.....some reaming but not to damaged......get the loose, barely hanging on stuff out. Get down to good material. Make sure very dry, no dampness. For clarification, I use the "Splash Zone" on gel coat holes. For wood I use the two part epoxy. I found a hardware store "Loctite" epoxy instant mix product that mixes both materials in the syringe tip for a cleaner operation. I go with two (or more) applications to prevent a mess if filling all at once leaves a bad drip. In both instances I use a small splinter if re-using the hole. Too large a splinter and it throws off the pre drilling for a screw.

Garris