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I recommend filling the screw holes with thickened epoxy paste or even marine tex. You should also chamfer/bevel the edges of all new holes anytime you drill into gel to prevent spider cracks. Another benefit, you can control/shorten the amount of curing time of the epoxy vs. waiting overnite with silicone.

Whatever you do, don't use 5200 for sealing the screws. If it ever has to come off again, you'll end up wringing off half the screws heads. 4200, life caulk or plain old marine silicone will seal the screws. If you are using the black flexable rubrail let it sit in the sun to soften, it makes it easier to work with